F*CK Getting Old

Supplement Database

Fadogia Agrestis

600 mg · Daily

Evidence

1.0/5
Human Studies
0
Animal Studies
10
Clinical Status
Dietary Supplement
Confidence
Low
Long-Term Safety
Unknown — no published human trials at all; some animal data raises unresolved safety questions at high doses

What this score is: a measure of how much research exists and how far along it is (animal-only vs. human trials, research-stage vs. FDA approved) — not how safe, effective, or worth trying a compound is. A low score usually means “early stage” or “understudied,” not “bad.” A high score doesn’t mean “better” for your goals than a lower-scored one.

This is not my personal rating of the compound, not a recommendation, and not medical advice. It’s a general research synthesis for informational purposes only, not a live literature count. See the linked research and talk to a licensed clinician before making decisions based on it.

Mechanism

Fadogia Agrestis is an herbal extract that has become popular in men's health/fitness marketing as a testosterone booster, largely on the strength of a small number of rodent studies. Unlike Tongkat Ali, it has essentially no published human clinical trial data — its popularity has substantially outpaced the actual research behind it.

Common Protocols

  • 300–600 mg daily of extract, per product labeling — there is no clinically established human dosing, only marketing convention

Side Effects

  • No systematic human safety data exists at all
  • Animal studies at high doses have raised unresolved questions about testicular tissue effects

Interactions

  • No formal human interaction data exists

Practical Details

Cost
$$
Typical Dose
600 mg
Storage
Store in a cool, dry place

Research Links

Popular T-booster on social media; human evidence is essentially absent