Fadogia Agrestis
600 mg · Daily

Robert
Founder, F*CK Getting Old — independent researcher, not a medical professional.
Last reviewed · 2 cited sources
Evidence
- Human Studies
- 0
- Animal Studies
- 10
- Clinical Status
- Dietary Supplement
- Confidence
- Low
- Long-Term Safety
- Unknown — no published human trials at all; some animal data raises unresolved safety questions at high doses
What this score is: a measure of how much research exists and how far along it is (animal-only vs. human trials, research-stage vs. FDA approved) — not how safe, effective, or worth trying a compound is. A low score usually means “early stage” or “understudied,” not “bad.” A high score doesn’t mean “better” for your goals than a lower-scored one.
This is not my personal rating of the compound, not a recommendation, and not medical advice. It’s a general research synthesis for informational purposes only, not a live literature count. See the linked research and talk to a licensed clinician before making decisions based on it.
Mechanism
Fadogia Agrestis is an herbal extract that has become popular in men's health/fitness marketing as a testosterone booster, largely on the strength of a small number of rodent studies. Unlike Tongkat Ali, it has essentially no published human clinical trial data — its popularity has substantially outpaced the actual research behind it.
Common Protocols
- 300–600 mg daily of extract, per product labeling — there is no clinically established human dosing, only marketing convention
Side Effects
- No systematic human safety data exists at all
- Animal studies at high doses have raised unresolved questions about testicular tissue effects
Interactions
- No formal human interaction data exists
Practical Details
- Cost
- $$
- Typical Dose
- 600 mg
- Storage
- Store in a cool, dry place
Key Studies & Reviews
- Yakubu MT et al. (2008). Effects of oral administration of aqueous extract of Fadogia agrestis stem on testicular function indices of male rats. J Ethnopharmacol. PMID 18023305.
- Yakubu MT et al. (2005). Aphrodisiac potentials of the aqueous extract of Fadogia agrestis stem in male albino rats. Asian J Androl. PMID 16281088.
Search the Research
Fadogia Agrestis FAQ
What is the typical Fadogia Agrestis dosage?
Commonly reported protocols: 300–600 mg daily of extract, per product labeling — there is no clinically established human dosing, only marketing convention. Our reference entry uses 600 mg, Daily. These reflect protocols reported in research and user communities, not a medical recommendation — dosing should be decided with a clinician.
What are the side effects of Fadogia Agrestis?
Reported side effects include: No systematic human safety data exists at all; Animal studies at high doses have raised unresolved questions about testicular tissue effects.
Is Fadogia Agrestis FDA approved?
Fadogia Agrestis is sold as a dietary supplement. The FDA does not approve supplements for safety or effectiveness before they are sold, so third-party tested brands are worth seeking out.
How much research is there on Fadogia Agrestis?
Our evidence profile counts roughly 0 human and 10 animal studies, with low overall confidence. Long-term safety: Unknown — no published human trials at all; some animal data raises unresolved safety questions at high doses.
Does Fadogia Agrestis interact with other drugs or supplements?
No formal human interaction data exists.
Related compounds
Popular T-booster on social media; human evidence is essentially absent