Boron
10 mg · Daily
Robert
Founder, F*CK Getting Old — independent researcher, not a medical professional.
Last reviewed · 2 cited sources
Evidence
- Human Studies
- 10
- Animal Studies
- 15
- Clinical Status
- Dietary Supplement
- Confidence
- Low
- Long-Term Safety
- Limited — small trial sizes and short durations; standard doses appear safe but long-term data is thin
What this score is: a measure of how much research exists and how far along it is (animal-only vs. human trials, research-stage vs. FDA approved) — not how safe, effective, or worth trying a compound is. A low score usually means “early stage” or “understudied,” not “bad.” A high score doesn’t mean “better” for your goals than a lower-scored one.
This is not my personal rating of the compound, not a recommendation, and not medical advice. It’s a general research synthesis for informational purposes only, not a live literature count. See the linked research and talk to a licensed clinician before making decisions based on it.
Mechanism
Boron is a trace mineral studied in small trials for modestly reducing SHBG (raising free testosterone) and lowering inflammatory markers like CRP. The evidence base is small but reasonably consistent in the studies that exist; effect sizes are modest rather than dramatic.
Common Protocols
- 6–10 mg daily — doses much above this have less safety data and no clear added benefit
Side Effects
- Generally well-tolerated at studied doses
- GI upset at high doses
Interactions
- No well-characterized interactions at standard doses
Practical Details
- Cost
- $
- Typical Dose
- 10 mg
- Storage
- Store in a cool, dry place
Key Studies & Reviews
- Naghii MR et al. (2011). Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. J Trace Elem Med Biol. PMID 21129941.
- Pizzorno L (2015). Nothing boring about boron. Integr Med (Encinitas). PMID 26770156.
Search the Research
Boron FAQ
What is the typical Boron dosage?
Commonly reported protocols: 6–10 mg daily — doses much above this have less safety data and no clear added benefit. Our reference entry uses 10 mg, Daily. These reflect protocols reported in research and user communities, not a medical recommendation — dosing should be decided with a clinician.
What are the side effects of Boron?
Reported side effects include: Generally well-tolerated at studied doses; GI upset at high doses.
Is Boron FDA approved?
Boron is sold as a dietary supplement. The FDA does not approve supplements for safety or effectiveness before they are sold, so third-party tested brands are worth seeking out.
How much research is there on Boron?
Our evidence profile counts roughly 10 human and 15 animal studies, with low overall confidence. Long-term safety: Limited — small trial sizes and short durations; standard doses appear safe but long-term data is thin.
Does Boron interact with other drugs or supplements?
No well-characterized interactions at standard doses.
Related compounds
Trace mineral studied for modest effects on free testosterone and inflammation markers