DSIP (Delta Sleep-Inducing Peptide)
100 mcg · Nightly
Robert
Founder, F*CK Getting Old — independent researcher, not a medical professional.
Last reviewed · 2 cited sources
Evidence
- Human Studies
- 5
- Animal Studies
- 15
- Clinical Status
- Research
- Confidence
- Low
- Long-Term Safety
- Unknown — old, small studies with inconsistent results and essentially no modern controlled human trials
What this score is: a measure of how much research exists and how far along it is (animal-only vs. human trials, research-stage vs. FDA approved) — not how safe, effective, or worth trying a compound is. A low score usually means “early stage” or “understudied,” not “bad.” A high score doesn’t mean “better” for your goals than a lower-scored one.
This is not my personal rating of the compound, not a recommendation, and not medical advice. It’s a general research synthesis for informational purposes only, not a live literature count. See the linked research and talk to a licensed clinician before making decisions based on it.
Mechanism
DSIP was originally isolated from rabbit brain in the 1970s and named for association with delta-wave (deep) sleep in early animal studies, though subsequent human research has produced inconsistent results and its mechanism is not well characterized. It is sold as a research chemical with limited modern clinical validation.
Common Protocols
- 100 mcg subcutaneous, taken shortly before bed, per informal research-community protocols — no established clinical dosing guideline exists
Side Effects
- Limited systematic data; anecdotal reports of vivid dreams
- Injection site irritation
Interactions
- No formal interaction data exists; caution combining with other sedating compounds
Practical Details
- Cost
- $
- Typical Vial Size
- 5 mg
- Storage
- Refrigerate after reconstitution
Key Studies & Reviews
- Graf MV, Kastin AJ (1986). Delta-sleep-inducing peptide (DSIP): an update. Peptides. PMID 3550726.
- Vgontzas AN et al. (1995). Delta sleep-inducing peptide in normal humans and in patients with sleep apnea and narcolepsy. Peptides. PMID 8532601.
Search the Research
DSIP (Delta Sleep-Inducing Peptide) FAQ
What is the typical DSIP (Delta Sleep-Inducing Peptide) dosage?
Commonly reported protocols: 100 mcg subcutaneous, taken shortly before bed, per informal research-community protocols — no established clinical dosing guideline exists. Our reference entry uses 100 mcg, Nightly. These reflect protocols reported in research and user communities, not a medical recommendation — dosing should be decided with a clinician.
What are the side effects of DSIP (Delta Sleep-Inducing Peptide)?
Reported side effects include: Limited systematic data; anecdotal reports of vivid dreams; Injection site irritation.
Is DSIP (Delta Sleep-Inducing Peptide) FDA approved?
DSIP (Delta Sleep-Inducing Peptide) is not FDA approved for human use and is generally sold as a research chemical, so purity and dosing are not regulated.
How much research is there on DSIP (Delta Sleep-Inducing Peptide)?
Our evidence profile counts roughly 5 human and 15 animal studies, with low overall confidence. Long-term safety: Unknown — old, small studies with inconsistent results and essentially no modern controlled human trials.
Does DSIP (Delta Sleep-Inducing Peptide) interact with other drugs or supplements?
No formal interaction data exists; caution combining with other sedating compounds.
How do I reconstitute DSIP (Delta Sleep-Inducing Peptide)?
A common setup is a 5 mg vial mixed with 2 mL of bacteriostatic water, which puts a 100 mcg dose at about 2 units on a U-100 insulin syringe. Use the reconstitution calculator with your own vial and dose to get exact numbers. Storage: Refrigerate after reconstitution.
Related compounds
Sleep-promoting peptide; name is somewhat misleading, mechanism not fully understood