F*CK Getting Old

Supplement Database

Taurine

2 g · Daily

Evidence

2.5/5
Human Studies
40
Animal Studies
50
Clinical Status
Dietary Supplement
Confidence
Low
Long-Term Safety
Well-tolerated in the human trials that exist (mostly athletic performance, not longevity); the longevity-specific evidence generating recent interest is still primarily animal data

What this score is: a measure of how much research exists and how far along it is (animal-only vs. human trials, research-stage vs. FDA approved) — not how safe, effective, or worth trying a compound is. A low score usually means “early stage” or “understudied,” not “bad.” A high score doesn’t mean “better” for your goals than a lower-scored one.

This is not my personal rating of the compound, not a recommendation, and not medical advice. It’s a general research synthesis for informational purposes only, not a live literature count. See the linked research and talk to a licensed clinician before making decisions based on it.

Mechanism

Taurine is a conditionally essential amino acid involved in bile salt formation, cellular osmoregulation, and antioxidant defense. A widely covered 2023 animal study found declining taurine levels correlated with aging markers and that supplementation extended healthspan in mice — human evidence for longevity specifically is still very preliminary despite the popular press coverage.

Common Protocols

  • 1–3 g daily, commonly split into doses
  • Athletic-performance trials have used similar doses around exercise

Side Effects

  • Generally very well-tolerated
  • Mild GI upset at high doses

Interactions

  • No well-characterized interactions at standard doses

Practical Details

Cost
$
Typical Dose
2 g
Storage
Store in a cool, dry place

Research Links

Amino acid with renewed longevity research interest; also a common energy-drink ingredient at much lower doses