Kisspeptin-10
100 mcg · As directed/research protocol
Evidence
- Human Studies
- 20
- Animal Studies
- 40
- Clinical Status
- Research
- Confidence
- Low
- Long-Term Safety
- Studied mostly in short, monitored clinical research infusions; no long-term safety data for the self-administered subcutaneous use common in research-chemical circles
What this score is: a measure of how much research exists and how far along it is (animal-only vs. human trials, research-stage vs. FDA approved) — not how safe, effective, or worth trying a compound is. A low score usually means “early stage” or “understudied,” not “bad.” A high score doesn’t mean “better” for your goals than a lower-scored one.
This is not my personal rating of the compound, not a recommendation, and not medical advice. It’s a general research synthesis for informational purposes only, not a live literature count. See the linked research and talk to a licensed clinician before making decisions based on it.
Mechanism
Kisspeptin-10 is the active fragment of kisspeptin, a neuropeptide that sits upstream of GnRH and drives the entire hypothalamic-pituitary-gonadal axis. It has been used in clinical research settings (often via controlled IV infusion, not home subcutaneous injection) to study fertility and reproductive hormone regulation.
Common Protocols
- Human research has generally used controlled IV infusion protocols in clinical settings, not the self-directed subcutaneous dosing common with other research peptides — self-administered dosing is not well established
Side Effects
- Flushing
- Nausea reported in some infusion studies
- Effects on hormone levels are the whole point of the mechanism, which cuts both ways outside a monitored setting
Interactions
- Directly affects LH/FSH/testosterone or estrogen output — combining with other hormone-modulating compounds without monitoring is poorly understood
Practical Details
- Cost
- $$
- Typical Vial Size
- 5 mg
- Storage
- Refrigerate after reconstitution
Research Links
Upstream regulator of the reproductive hormone axis; mostly a research tool