F*CK Getting Old

Peptide Database

HGH Fragment 176-191

250–500 mcg · Daily

Evidence

1.5/5
Human Studies
3
Animal Studies
20
Clinical Status
Research
Confidence
Low
Long-Term Safety
Unknown — human evidence for the fat-loss claim specifically is thin, and long-term safety data is essentially absent

What this score is: a measure of how much research exists and how far along it is (animal-only vs. human trials, research-stage vs. FDA approved) — not how safe, effective, or worth trying a compound is. A low score usually means “early stage” or “understudied,” not “bad.” A high score doesn’t mean “better” for your goals than a lower-scored one.

This is not my personal rating of the compound, not a recommendation, and not medical advice. It’s a general research synthesis for informational purposes only, not a live literature count. See the linked research and talk to a licensed clinician before making decisions based on it.

Mechanism

HGH Fragment 176-191 is a synthetic fragment of the C-terminal region of growth hormone that, in animal studies, retains GH's fat-metabolizing effect without significantly affecting blood sugar, IGF-1, or tissue growth the way full-length GH does. Human data supporting this fat-loss-specific effect is far thinner than the animal literature.

Common Protocols

  • 250–500 mcg subcutaneous daily, often on an empty stomach
  • Sometimes injected near targeted fat deposits based on unproven "spot reduction" theory

Side Effects

  • Injection site irritation
  • Limited systematic human safety data

Interactions

  • No formal interaction data exists

Practical Details

Cost
$$
Typical Vial Size
5 mg
Storage
Refrigerate after reconstitution

Research Links

Fat-loss-targeted fragment of growth hormone; does not raise GH itself